The UMD-MYO7A mutations database
Record ID: 439

Mutation description (Allele #2)


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.3265delGp.Ala1089ProfsX19HeterozygousMutation

wt codonwt aamutant codonmutant aamutational eventmutation type
GCCAladel1aFs.Stop at 1107Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
 

Mutation(s) on the other allele: c.3260T>C

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionGeographic origin
YE0100100011ProbandMaleYEMEN

Phenotypic groupDisease
TypeI Usher 

Clinical data


Symptom

Reference


Reference IDPubMed IDReference
1410364543
Adato - Bonne-Tamir 1999