The UMD-MSH2 mutations database
Lys to Stop mutations

Protein nomenclature	cDNA Nomenclature	Exon	Codon	Structure	HCD	Rearrangement	Mutation type	Mutational event	# records
p.Lys59X	c.175A>T	1	59	Mismatch binding		Small rearrangement	Tv	A->T	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 364 6_605058_B00059365_S2626 - 6
p.Lys65X	c.193A>T	1	65	Mismatch binding		Small rearrangement	Tv	A->T	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 366 6_611355_B00069847_S 3896 - 6
p.Lys490X	c.1468A>T	9	490	EXO1 stabilization		Small rearrangement	Tv	A->T	13
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 31 2_02-ACT2630_18399_18399 - 2 360 6_608137_20082835_S5149 - 6 694 19_12005_12005-001_12005- - 19 695 19_12005_12005-002_12005- - 19 2318 SO_-1694---G00159 - 71 2405 SO_-2421---G01764 - 71 2489 SO_-1694---G03672 - 71 2542 SO_-1694---G05518 - 71 2595 SO_-1694---G06428 - 71 2596 SO_-1694---G06430 - 71 2622 SO_-1694---G06850 - 71 2659 SO_-1694---G07350 - 71 2725 SO_-5401---G08254 - 71
p.Lys567X	c.1699A>T	11	567	Lever		Small rearrangement	Tv	A->T	9
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 3101 31_H1869H1869-1H1869-1A - 31 284 5_1998009_19980613_--- - 5 285 5_1998009_20032926_AAA899 - 5 286 5_1998009_20032925_AAA990 - 5 287 5_2009452_20094819_AAD659 - 5 1535 7_15451460E03149 - 7 2315 7_1545488E980027 - 7 2517 SO_-3668---G05082 - 71 2946 19_L11.06116059113232 - 19
p.Lys918X	c.2752A>T	16	918	MSH3/MSH6 interaction		Small rearrangement	Tv	A->T	1
UMD_id Sample ID Gender Mutation status Geographic origin Phenotypic group References 215 4_H-JCS0206_17085_765 - 4