The UMD-MSH2 mutations database
Record ID: 364

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.175A>Tp.Lys59X

wt codonwt aamutant codonmutant aamutational eventmutation type
AAGLysTAGStopA->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Mismatch binding Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient status
6_605058_B00059365_S2626Relative

Clinical data


Symptom

Reference


Reference IDReference
6Unpublished data