The UMD-MEN1 mutations database
Record ID: 1846

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.512G>Ap.Arg171GlnNEUTRAL

wt codonwt aamutant codonmutant aamutational eventmutation type
CGGArgCAGGlnG->ATs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NMH,HD,NM Yes, non coding strandYes

Other deleterious mutation(s) reported for this sample: c.544G>T; c.1_18del ?

Other variation(s) reported for this sample: ; ; c.1299T>C; ; c.1254C>T; c.IVS9-115G>C (c.1351-115G>C)

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): BstN I, EcoR II
Lost restriction site(s): Hpa II, Msp I

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 59 (Probable polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
Proband

Phenotypic groupDisease
Not availablePlease contact curator

Reference


Reference IDPubMed IDReference
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