The UMD-MEN1 mutations database
Record ID: 1677

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1299T>Cp.His433HisBenign

wt codonwt aamutant codonmutant aamutational eventmutation type
CATHisCACHisT->CTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Pem,NM,RP,HD,CH NoNo

Other deleterious mutation(s) reported for this sample: c.544G>T; c.1_18del ?

Other variation(s) reported for this sample: ; ; ; c.512G>A; c.1254C>T; c.IVS9-115G>C (c.1351-115G>C)

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): BsaA I, Mae II, Pml I
Lost restriction site(s): Nla III

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0 - 18 (Polymorphism)

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
Proband

Phenotypic groupDisease
Please contact curator

Reference


Reference IDPubMed IDReference
0Í