The UMD-MEN1 mutations database
Record ID: 1420

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.628_631delACAGp.Thr210SerfsX13HeterozygousCAUSAL

wt codonwt aamutant codonmutant aamutational eventmutation type
ACAThrdel4aFs.Stop at 222Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Ju,Sm,NMH,HD,NM Yes, coding strand

Other variation(s) reported for this sample: c.IVS1-6G>A (c.1-6G>A)

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionAge of onsetAge of DeathGeographic origin
01-MA26-O12I-ProbandMale40

Phenotypic groupDisease
ModeratePlease contact curator

Reference


Reference IDPubMed IDReference
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