UMD TP53

TP53

TP53 and cancer

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MUTP53LOAD

Welcome page

Transcription

Global view

Full report

Search MUTP53LOAD

 

 

 

 

 

 

 

 

 

 

What is MUTP53LOAD?

MUTP53LOAD stands forMutant p53 Loss Of Activity Database.

MUTP53LOAD is a totally new database that gathrered in a single repository functional data on p53 Mutants. Data have been extracted manually from the literature to prevent inacuracy and errors associated with automatic datamining.

Due to the complexity of the p53 protein and the high number of heterogeneous activities associated with mutant p53, loss of function have been grouped in 4 categories: Transcription, Structure, Cell Biology and Gain of function.


DN: Dominant Negative

Four different tools are availa

Tool 1: Transcription
Display the transcriptional activity for various p53RE (click here for an example of the output display).

Tool 2: Global view
Display a summary of p53 loss of activity for a p53 in simplified graphical output (click here for an example of the output display).

Tool 3: Full report
Display an exhaustive table of mutant p53 loss of activity (click here for an example of the output display).

Tool 4: Search MUTP53LOAD
Allow the user to find specific features in the MUTP53LOAD (click here for an example of the output display).