The UMD-MYO7A mutations database
Record ID: 944

Mutation description (Allele #2)


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.5004C>Gp.Tyr1668XHeterozygousMutation

wt codonwt aamutant codonmutant aamutational eventmutation type
TACTyrTAGStopC->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
SH3 NoNo

Mutation(s) on the other allele: c.6025delG

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): Csp6 I, Mae II, Rsa I

Patient and sample data


Sample IDPatient statusGenderTransmissionGeographic origin
FR0157014970ProbandFemaleFRANCE

Phenotypic groupDisease
TypeI Usher 

Clinical data


Symptom

Reference


Reference IDReference
1Unpublished data