The UMD-MYO7A mutations database
Record ID: 466

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.6025delGp.Ala2009ProfsX32HeterozygousMutation

wt codonwt aamutant codonmutant aamutational eventmutation type
GCCAladel1aFs.Stop at 2040Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
FERM 2 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionGeographic origin
US0201822192ProbandUnknownU.K.

Phenotypic groupDisease
TypeI Usher 

Clinical data


Symptom

Reference


Reference IDPubMed IDReference
1510930322
Bharadwaj - Dryja 2000