The UMD-MYO7A mutations database
Record ID: 247

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation statusVariation class
c.1005_1012delp.Arg336XHomozygousMutation

wt codonwt aamutant codonmutant aamutational eventmutation type
GCAAladel8cFs.Stop at 336Fr.

StructureKey Residue (HCD)Pyrimidin doubletCpG
Motor domain 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Patient and sample data


Sample IDPatient statusGenderTransmissionGeographic origin
FR0132006371ProbandMaleSENEGAL

Phenotypic groupDisease
TypeI Usher 

Clinical data


Symptom

Reference


Reference IDPubMed IDReference
2516679490
Roux - Claustres 2006