The UMD-MSH6 mutations database
Mutation c.IVS8+21T>C (c.3801+21T>C)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH6	MLH1	MSH2	MUTYH	APC
8_475989387208-241321	-	-	c.IVS5+3A>T (c.942+3A>T)	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case (47598-93872) : rectal cancer, age ?. No family data	25/09/15	8 (Nancy)	---
MMR function in tumor cells	MSI-H (47598-93872)	25/09/15	8 (Nancy)	---
Co-occurrence	MSH2:c.942+3A>T, p.? (47598-93872)	25/09/15	8 (Nancy)	---

Biological significance	Date	Comment
UV	25/09/15	---