The UMD-MSH6 mutations database
Mutation c.546delC

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH6	MLH1	MSH2	MUTYH	APC
4_H14194335405117	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Colorectal cancer at the age of 35; brother : colorectal cancer at the age of 37 (H14194)	23/03/15	4 (Lyon)	---
MMR function in tumor cells	MSI-H, MSH6- (H14194-33540)	23/03/15	4 (Lyon)	---

Biological significance	Date	Comment
Causal	25/03/15	---