TheUMD-MSH2 mutations database
Large rearrangement: c.367_1386del (deletion from exon 3 to 8)

Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_2443124431.00124431.001	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Sporadic colorectal cancer < 50 years old (24431.001)	13/05/14	19 (Rouen)	---
MMR function in tumor cells	MSI / MLH1+MSH2-MSH6- (24431.001)	13/05/14	19 (Rouen)	---

Biological significance	Date	Comment
Causal	22/05/14	---

Consequences of the mutation at the protein level No data available