TheUMD-MSH2 mutations database
Large rearrangement: c.212_366del (deletion from exon 2 to 2)

Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
8_431121473408-521111EGS	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Sporadic colorectal cancer < 50 years old (43112-14734)	27/04/12	8 (Nancy)	---
MMR function in tumor cells	MSI-H / MSH2-MSH6- (43112-14734)	27/04/12	8 (Nancy)	---

Biological significance	Date	Comment
Causal	5/06/14	---

Consequences of the mutation at the protein level No data available