TheUMD-MSH2 mutations database
Large rearrangement: c.1662_2805del (deletion from exon 11 to 16)

Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_4146_4146-001_4146-001	-	-	-	-	-
19_4146_4146-003_4146-003	-	-	-	-	-
4_JCS1001_24139_2970	-	-	-	-	-
8_461238692608-083131EGS	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSI-H / MSH2-MSH6- (46123-86926)	13/06/14	8 (Nancy)	---

Biological significance	Date	Comment
Causal	21/02/14	---

Consequences of the mutation at the protein level No data available