The UMD-MSH2 mutations database
Mutation c.IVS10-43C>T (c.1662-43C>T)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Alternative Branch Point?	tacacat	70.7 _	taTacat	46.9 _ *	-33.6 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
31_H459_H459-1_H459-1A	c.637delC (p.Leu213X)	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSS (H459-1)	26/10/15	31 (Montpellier)	---
Co-occurrence	MSH2: c.637delC; p.Leu213X (H459-1)	9/05/12	31 (Montpellier)	---

Biological significance	Date	Comment
UV	28/05/14	---