The UMD-MSH2 mutations database
Mutation c.IVS15+1G>A (c.2634+1G>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Donor	GAGgtttgt	84.4 _	GAGatttgt	57.6 _ *	-31.8 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
25_14534_P14534_1_ABD26	-	-	-	-	-
25_HCC-1365DURBRUNADK75	-	-	-	-	-
2_02-DDM999933464212312402	-	-	c.1409C>G (p.Ser470X)	-	-

Biological significance	Date	Comment
Causal	21/02/14	---