The UMD-MSH2 mutations database
Mutation c.IVS7+11A>G (c.1276+11A>G)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Cryptic Donor?	gtgattttg	38.6 _	gtggttttg	65.4 _ *	41 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_14769_14769-001_14769-	c.336C>A (p.Ser112Ser)	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Co-occurrence	MSH2 : c.336C>A, p.=	26/09/11	19 (Rouen)	---
Ex vivo analysis	Splicing reporter minigene pCAS: normal splicing	26/09/11	19 (INSERM U1079-Rouen)	---

Biological significance	Date	Comment
Neutral	26/09/11	---