The UMD-MSH2 mutations database
Mutation c.IVS15-3C>T (c.2635-3C>T)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	catgtgtttcagCA	82.3 _	catgtgttttagCA	74.6 _	-9.3 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
6_601146_20063661_S7476	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Amsterdam I - (late-onset Lynch-related tumors)	20/09/10	6 (Toulouse)	---
MMR function in tumor cells	MSI / MSH2-MSH6-	20/09/10	6 (Toulouse)	---

Biological significance	Date	Comment
UV	22/09/09	---