The UMD-MSH2 mutations database
Mutation c.IVS6-10T>A (c.1077-10T>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	aatttatttcagAT	85.1 _	aaattatttcagAT	81.9 _	-3.8 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
20_20-27472747-01---	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case : appendix cancer at the age of 31 (20-2747-01). Maternal grandmother : colorectal cancer at the age of 73.	28/08/15	20 (Clermont-Ferrand)	---

Biological significance	Date	Comment
UV	11/09/15	---