The UMD-MSH2 mutations database
Mutation c.IVS7+1G>A (c.1276+1G>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Donor	AAGgtaaca	84.7 _	AAGataaca	57.9 _ *	-31.7 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
4_12332---4272	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSI-H / MSH2-MSH6- (19853-001)	17/03/15	4 (Lyon)	---

Biological significance	Date	Comment
Causal	18/03/15	---