The UMD-MSH2 mutations database
Mutation c.IVS5+3A>C (c.942+3A>C)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Donor	CAGgtaaaa	99.2 _	CAGgtcaaa	81.1 _ *	-18.2 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
4_11194267663654	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
In vitro analysis	RT-PCR : loss of exon 5	26/03/12	4 (Lyon)	---
Clinical phenotype	Amsterdam I+	26/03/12	4 (Lyon)	---

Biological significance	Date	Comment
Causal	26/03/12	---