The UMD-MSH2 mutations database
Mutation c.IVS8-77T>G (c.1387-77T>G)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
2_02-DDM1123237144213308472	-	-	-	-	-
2_02-DDM3849_21496_21496	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSS / MLH1+MSH2+	19/09/09	2 (Villejuif)	---
Clinical phenotype	Sporadic colon cancer < 50 years old (+ late-onset uterus cancer in the family) (02-DDM11232)	1/07/14	2 (Villejuif)	---

Biological significance	Date	Comment
Likely Neutral	13/12/11	---