The UMD-MSH2 mutations database
Mutation c.IVS10-18T>C (c.1662-18T>C)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
5_201143820113682AAF518	-	-	-	-	-
5_2011438_20113682_AAF518	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Sporadic colorectal cancer < 50 years old	9/12/13	56 (Bordeaux)	---
MMR function in tumor cells	MSS (2011438-20113682)	31/03/12	5 (Bordeaux)	---
MMR function in tumor cells	MSS / MLH1+MSH2+MSH6+	9/12/13	5 (Bordeaux)	---
In vitro analysis	RT-PCR : normal splicing	9/12/13	5 (Bordeaux)	---

Biological significance	Date	Comment
Neutral	9/12/13	---