The UMD-MSH2 mutations database
Mutation c.IVS10+1G>T (c.1661+1G>T)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Donor	CAGgtttgc	84 _	CAGttttgc	57.2 _ *	-31.9 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
31_H145_H145_1_H145_1_A	-	-	-	-	-
31_H145_H145_4_H145_4_A	-	-	-	-	-
31_H145_H145_5_H145_5_A	-	-	-	-	-
31_H145_H145_6_H145_6_A	-	-	-	-	-
41_HNPCC152_HNPCC152001_-	c.IVS9-9A>T (c.1511-9A>T) c.IVS10+12G>A (c.1661+12G>A)	-	-	-	-
5_2006140_20061991_AAB201	-	-	-	-	-
7_-5945---E050593	c.2801C>T (p.Thr934Met)	-	-	-	-
7_-59453982E050593	c.IVS1+9C>G (c.211+9C>G) c.IVS9-9A>T (c.1511-9A>T) c.IVS10+12G>A (c.1661+12G>A) c.2801C>T (p.Thr934Met)	-	-	-	-
7_5008 (F501)4169E050819	c.2801C>T (p.Thr934Met)	c.655A>G (p.Ile219Val)	-	-	-

Biological significance	Date	Comment
Causal	21/02/14	---