The UMD-MSH2 mutations database
Mutation c.IVS7-10T>C (c.1277-10T>C)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	actttcttttagGA	84.4 _	accttcttttagGA	83.7 _	-0.8 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
SO_-5037---G07710	c.1222dup (p.Tyr408LeufsX9)	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Co-occurrence	MSH2 : c.1222dup, p.Tyr408LeufsX9 (patient A)	28/01/04	SO (Marseille)	---

Biological significance	Date	Comment
UV	9/07/15	---