The UMD-MSH2 mutations database
Mutation c.IVS3-1G>C (c.646-1G>C)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	ctttcaaaatagAT	77.8 _	ctttcaaaatacAT	48.9 _ *	-37.2 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_11219_11219-001_11219-	-	-	-	-	-
19_11219_11219-002_11219-	-	-	-	-	-
4_H-JCS0408_17830_1094	-	-	-	-	-

Biological significance	Date	Comment
Causal	21/02/14	---