The UMD-MSH2 mutations database
Mutation c.IVS15-11A>G (c.2635-11A>G)


Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)
Cryptic Donor?
cacatgtgt
52.2 _
cacgtgtgt
79 _ *
34 %


     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)
Sample IDMSH2MLH1MSH6MUTYHAPC
7_-62245184E060402c.IVS1+9C>G (c.211+9C>G)
c.IVS10+12G>A (c.1661+12G>A)
c.IVS12-6T>C (c.2006-6T>C)
c.IVS14-19A>G (c.1668-19A>G)
c.1963A>G (p.Ile655Val)
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Biological significanceDate Comment
UV6/06/07---