The UMD-MSH2 mutations database
Mutation c.IVS7+2T>A (c.1276+2T>A)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Donor	AAGgtaaca	84.7 _	AAGgaaaca	57.9 _ *	-31.7 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
17_F96015__2731	-	-	-	-	-
31_H1179_H1179-1_H1179-1A	-		-	-	-
31_H1179_H1179-1_H1179-1B	-	-	-	-	-
4_H95H007_17764_600	-	-	-	-	-
4_JCS1403333444958	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSI-H / MSH2-MSH6- (JCS1403-33344)	17/03/15	4 (Lyon)	---

Biological significance	Date	Comment
Causal	21/02/14	---