The UMD-MSH2 mutations database
Mutation c.IVS14+10A>C (c.2458+10A>C)



     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)
Sample IDMSH2MLH1MSH6MUTYHAPC
7_1030284E2K267c.2546T>G (p.Leu849Arg)c.IVS14-19A>G (c.1668-19A>G)c.IVS5+14A>T (c.3438+14A>T)
c.87C>A (p.Arg29Arg)
c.276A>G (p.Pro92Pro)
c.540T>C (p.Asp180Asp)		--
7_1099289E2K272c.974C>T (p.Ser325Phe)c.483G>A (p.Thr161Thr)
c.IVS14-19A>G (c.1668-19A>G)		---
7_1141293E2K275c.157G>A (p.Ala53Thr)
c.IVS10+12G>A (c.1661+12G>A)
c.2546T>G (p.Leu849Arg)		gt;A (p.Glu37Lys)
c.483G>A (p.Thr161Thr)
c.IVS13+14G>A (c.1558+14G>A)
c.IVS14-19A>G (c.1668-19A>G)
c.655A>G (p.Ile219Val)		---
7_20588E2K036c.IVS9-9A>T (c.1511-9A>T)
c.IVS10+12G>A (c.1661+12G>A)		c.483G>A (p.Thr161Thr)
c.655A>G (p.Ile219Val)
c.2146G>A (p.Val716Met)		---
7_20699E2K037-c.655A>G (p.Ile219Val)---
7_2432353E01034c.974C>T (p.Ser325Phe)c.2136G>A (p.Trp712X)---
7_38732077E040292c.IVS1-4del (c.212-4del)c.655A>G (p.Ile219Val)---
7_40352204E040427c.157G>A (p.Ala53Thr)c.IVS14-19A>G (c.1668-19A>G)
c.655A>G (p.Ile219Val)		---
7_42812412E040559c.148G>A (p.Ala50Thr)c.IVS14-19A>G (c.1668-19A>G)
c.655A>G (p.Ile219Val)		---
7_4335 (04K224)2463E04059c.IVS10+12G>A (c.1661+12G>A)----

Biological significanceDate Comment
UV6/06/07---