The UMD-MSH2 mutations database
Mutation c.IVS4-2A>C (c.793-2A>C)

Splice site type	Wild type sequence	CV	Mutant type sequence	CV	Variation (%)
Acceptor	tcttaattttagGT	84 _	tcttaattttcgGT	55 _ *	-34.5 %

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
37_F07.017_5191_55701	-	-	-	-	-
37_F07.017_6438_61311	-	-	-	-	-
37_F07.017_8293_75062	-	-	-	-	-
37_L01.0420198138247/139900	-	-	-	-	-
37_L01.04_906_3133	-	-	-	-	-
37_L04.11_1774_22924	-	-	-	-	-
37_L04.11_2447_26542	-	-	-	-	-
37_L04.11_2589_28309	-	-	-	-	-
37_L04.11_2664_29029	-	-	-	-	-

Biological significance	Date	Comment
Causal	21/02/14	---