The UMD-MSH2 mutations database
Mutation c.IVS4-23G>A (c.793-23G>A)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
2_02-ACT1936_14831_14831	c.380A>G (p.Asn127Ser)	-	-	-	-
2_02-DDM2676_18508_18508	c.380A>G (p.Asn127Ser)	-	-	-	-
2_02-DDM3108_16165_16165	-	-	-	-	-
2_PLP-HEGP EXT53_15561_15	c.380A>G (p.Asn127Ser)	-	-	-	-
37_P08.14717667677	c.380A>G (p.Asn127Ser)	c.IVS5-51T>C (c.454-51T>C)	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Co-occurrence	MSH2:c.380A>G, p.Asn127Ser (P08.14-7176)	31/03/15	37 (Lille)	---
Allele frequency	rs17224255 : 2.2% heterozygotes, no homozygotes AA	19/09/09	dbSNP	rs17224255

Biological significance	Date	Comment
Neutral	29/09/09	---