The UMD-MSH2 mutations database
Mutation c.IVS2-27A>C (c.367-27A>C)

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
2_02-DDM7122_30036_30036	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Ex vivo analysis	Splicing reporter minigene pCAS: normal splicing	9/07/15	19 (INSERM U1079-Rouen)	---
In vitro analysis	"RT-PCR (lymphocytes; +/- puromycine) : normal splicing, both alleles expressed"	9/07/15	2 (Villejuif) 19 (INSERM U1079-Rouen)	---

Biological significance	Date	Comment
Neutral	9/07/15	---