The UMD-MSH2 mutations database
Mutation c.970C>T

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_11134_11134-001_11134-	-	-	-	-	-
4_JCS1224293554272	-	-	-	-	-
5_2013240AAH587	-	-	-	-	-
7_-2515---E050131	-	-	-	-	-
7_-25153317E050131	-	-	-	-	-
SO_-2515---G01996	-	-	-	-	-
SO_-2515---G01997	-	-	-	-	-
SO_-2515---G02001	-	-	-	-	-
SO_-2515---G03246	-	-	-	-	-
SO_-2515---G03410	-	-	-	-	-
SO_-4670---G07010	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
MMR function in tumor cells	MSI-H / MSH2-MSH6- (2013240-AAH587)	13/06/14	5 (Bordeaux)	---
Clinical phenotype	Colorectal cancer at the age of 32 (family history of cancers) (JCS1224)	17/03/15	4 (Lyon)	---

Biological significance	Date	Comment
Causal	21/02/14	---