The UMD-MSH2 mutations database
Mutation c.2152C>T

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_13338_13338-001_13338-	-	-	-	-	-
19_2723427234-00127234-001	-	-	-	-	-
2_02-DDM6217_26383_26383	-	-	-	-	-
41_HNPCC079_HNPCC079001_-	c.IVS12-6T>C (c.2006-6T>C)	-	-	-	-
5_2002201_20024934_---	-	-	-	-	-
SO_-3839---G05384	-	-	-	-	-
SO_-3839---G06533	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Two colorectal cancers at the ages of 62 and 67 (27234-001)	17/04/15	19 (Rouen)	---
MMR function in tumor cells	MSI / MSH2-MSH6- (27234-001)	17/04/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	21/02/14	---