The UMD-MSH2 mutations database
Mutation c.1676delT

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_17215_17215-001_17215-	-	-	-	-	-
41_HNPCC036_HNPCC036001_-	-	-	-	-	-
7_-6042---E051173	-	c.52C>T (p.Arg18Cys)	-	-	-
7_-60424485E051173	c.IVS1+9C>G (c.211+9C>G) c.IVS10+12G>A (c.1661+12G>A) c.IVS12-6T>C (c.2006-6T>C)	c.IVS14-19A>G (c.1668-19A>G) c.52C>T (p.Arg18Cys) c.655A>G (p.Ile219Val)	-	-	-
8_F31991796608-500011BA	-	c.IVS9+10A>G (c.790+10A>G)	-	-	-
SO_-4778---G07163	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Amsterdam II+ (F3199-17966)	27/04/12	8 (Nancy)	---
Clinical phenotype	MLH1 : c.790+10A>G; p.? (F3199-17966)	27/04/12	8 (Nancy)	---

Biological significance	Date	Comment
Causal	21/02/14	---