The UMD-MSH2 mutations database
Mutation c.388C>T

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
4_CH1009250863219	-	-	-	-	-
6_610113_B68566_S9442	-	-	-	-	-
8_443967918908-646021EGS	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Multiple Lynch-related cancers (endometrium + colon) < 50 years old (1 patient : 44396-79189)	27/04/12	8 (Nancy)	---
MMR function in tumor cells	MSI-H (colon) (44396-79189)	27/04/12	8 (Nancy)	---

Biological significance	Date	Comment
Causal	21/02/14	---