The UMD-MSH2 mutations database
Mutation c.449_522del

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_1908919089-00119089-001	-	-	c.333C>T (p.Tyr111Tyr)	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Co-occurrence	Index case (19089-001) : colorectal cancers at the ages of 44 and 47	25/09/15	19 (Rouen)	---
Co-occurrence	MSI / MSH2-MSH6- (19089-001)	25/09/15	19 (Rouen)	---
Co-occurrence	MSH6:c.333C>T, p.= (19089-001)	25/09/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	25/09/15	---