The UMD-MSH2 mutations database
Mutation c.1753_1756delTCTT

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
2_02-OCN1331642498215047440	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case (02-OCN13316-42498) : colon cancer at the age of 52 + duodenal cancer at the age of 56. Paternal cousin : gastric cancer at the age of 55	1/09/15	2 (Villejuif)	---
MMR function in tumor cells	MSH2- (02-OCN13316-42498)	1/09/15	2 (Villejuif)	---

Biological significance	Date	Comment
Causal	9/09/15	---