The UMD-MSH2 mutations database
Mutation c.2131C>T

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_2689426894-00126894-001	-	-	-	-	-
19_7534_7534-001_7534-001	-	-	-	-	-
33_TNN 251__03-1129	-	-	-	-	-
5_2005331_P0028855_AAA866	-	-	-	-	-
6_601015_200600882_S6209	-	-	-	-	-
6_606229_200605863_S7035	-	-	-	-	-
7_-36903927E050548	-	-	-	-	-
SO_-1126---G00832	-	-	-	-	-
SO_-1126---G01723	-	-	-	-	-
SO_-1126---G03445	-	-	-	-	-
SO_-1126---G05912	-	-	-	-	-
SO_-1126---G06637	-	-	-	-	-
SO_-2343---G01316	-	-	-	-	-
SO_-2343---G02698	-	-	-	-	-
SO_-2971---G02985	-	-	-	-	-
SO_-3690---G06404	-	-	-	-	-
SO_-4608---G06915	-	-	-	-	-
SO_-473---G00211	-	-	-	-	-
SO_-473---G01542	-	-	-	-	-
SO_-653---G01497	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Three synchronous colorectal cancer at the age of 40 (26894-001)	17/04/15	19 (Rouen)	---
MMR function in tumor cells	MSI / MSH2-MSH6- (26894-001)	17/04/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	21/02/14	---