The UMD-MSH2 mutations database
Mutation c.1901T>G

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
19_2798227982-00127982-001	-	-	-	-	-
5_2004081_---_---	c.IVS6-10T>C (c.1077-10T>C) c.IVS12-6T>C (c.2006-6T>C)	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case (27982-001) : rectal cancer at the age of 33	25/09/15	19 (Rouen)	---
MMR function in tumor cells	MSH2-MSH6- (27982-001)	25/09/15	19 (Rouen)	---

Biological significance	Date	Comment
Causal	21/02/14	---