The UMD-MSH2 mutations database
Mutation c.2235_2237delAAT

     Data for this mutation

Co occurence of MLH1, MSH2, MSH6, MUTYH and APC mutations (Pathogenic mutations, Unclassified variants, Non-pathogenic variation)

Sample ID	MSH2	MLH1	MSH6	MUTYH	APC
41_HNPCC019_HNPCC019002_-	-	-	-	-	-

Complementary data about this mutation

Analysis	Result	Date	Origin	PMID/dbSNP
Clinical phenotype	Index case : uterine cancer at the age of 56, colon and pancreatic cancers at the age of 60. Son : colon cancer at the age of 33. Grandfather : oesophagal cancer at the age of 56 (HNPCC109)	9/12/14	41 (HEGP)	---
MMR function in tumor cells	MSH2- (colon tumor) (HNPCC109)	12/06/07	41 (HEGP)	---

Biological significance	Date	Comment
UV	6/06/07	---