The UMD-MSH2 mutations database
Record ID: 872

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.885C>Gp.Asp295Glu

wt codonwt aamutant codonmutant aamutational eventmutation type
GACAspGAGGluC->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
EXO1 stabilization Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.990.16 (non pathogenous)29 (Polymorphism)

Patient and sample data


Sample IDPatient status
19_15422_15422-001_15422-Relative

Clinical data


Symptom

Reference


Reference IDReference
19Unpublished data