The UMD-MSH2 mutations database
Record ID: 363

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.1701A>Tp.Lys567Asn

wt codonwt aamutant codonmutant aamutational eventmutation type
AAALysAATAsnA->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
EXO1 stabilization Yes, non coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
10.15 (non pathogenous)59 (Probable polymorphism)

Patient and sample data


Sample IDPatient status
6_606099_199401479_S3063Relative

Clinical data


Symptom

Reference


Reference IDReference
6Unpublished data