The UMD-MSH2 mutations database
Record ID: 328

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.2728C>Ap.Gln910Lys

wt codonwt aamutant codonmutant aamutational eventmutation type
CAGGlnAAGLysC->ATv

StructureKey Residue (HCD)Pyrimidin doubletCpG
MSH3/MSH6 interaction NoNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.990.79 (non pathogenous)41 (Polymorphism)

Patient and sample data


Sample IDPatient status
5_2009236_20092612_AAD369Relative

Clinical data


Symptom

Reference


Reference IDReference
5Unpublished data