The UMD-MSH2 mutations database
Record ID: 2655

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.55T>Cp.Phe19Leu

wt codonwt aamutant codonmutant aamutational eventmutation type
TTCPheCTCLeuT->CTs

StructureKey Residue (HCD)Pyrimidin doubletCpG
Mismatch binding Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.870.00 (pathogenous)53 (Probable polymorphism)

Patient and sample data


Sample IDPatient status
SO_-4866---G07330Relative

Clinical data


Symptom

Reference


Reference IDReference
71Unpublished data