The UMD-MSH2 mutations database
Record ID: 230

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.698C>Gp.Ser233Cys

wt codonwt aamutant codonmutant aamutational eventmutation type
TCCSerTGCCysC->GTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Connector Yes, coding strandNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.990.01 (pathogenous)64 (Probable polymorphism)

Patient and sample data


Sample IDPatient status
4_7284_20930_2214Relative

Clinical data


Symptom

Reference


Reference IDReference
4Unpublished data