The UMD-MSH2 mutations database
Record ID: 2249

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.IVS14+8C>T (c.2458+8C>T)

wt codonwt aamutant codonmutant aamutational eventmutation type
GGTGlyspl+8Spl.C>T

StructureKey Residue (HCD)Pyrimidin doubletCpG
ATPase 

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Impact on splicing
Splice site type Wild type sequence CV Mutant type sequence CV Variation (%)

Patient and sample data


Sample IDPatient status
7_1243412962E101800Relative

Clinical data


Symptom

Reference


Reference IDReference
7Unpublished data