The UMD-MSH2 mutations database
Record ID: 224

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.62G>Tp.Arg21Leu

wt codonwt aamutant codonmutant aamutational eventmutation type
CGCArgCTCLeuG->TTv

StructureKey Residue (HCD)Pyrimidin doubletCpG
Mismatch binding NoNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.870.02 (pathogenous)87 (Pathogenous)

Patient and sample data


Sample IDPatient status
4_Gr2007-122_28317_4026Relative

Clinical data


Symptom

Reference


Reference IDReference
4Unpublished data