The UMD-MSH2 mutations database
Record ID: 2024

Mutation description


Variation name (cDNA level)Variation name (protein level)Variation status
c.2801C>Ap.Thr934Lys

wt codonwt aamutant codonmutant aamutational eventmutation type
ACGThrAAGLysC->ATv

StructureKey Residue (HCD)Pyrimidin doubletCpG
MSH3/MSH6 interaction NoNo

Mutation impact


At the mRNA levelOn restriction map
New restriction site(s): none
Lost restriction site(s): none

Conservation (0-1)SIFT (0-1)UMD-predictor (0-100)
0.070.03 (pathogenous)86 (Pathogenous)

Patient and sample data


Sample IDPatient status
7_-60814447E051175Relative

Clinical data


Symptom

Reference


Reference IDReference
7Unpublished data